Novel putative enhancer regions aroundSox2. Plot showing novel putative enhancers around the Sox2 gene. The Enh and PrL probabilities of 1 kb bins are shown in red and blue bars, respectively. Only bins with probabilities greater than 0.8 are displayed for higher stringency, and the y-axis scale is from 0.5 to 1. A lincRNA approximately 100 kb downstream of Sox2 near the distal enhancer cluster is shown in black. Transcription factors peaks identified using the SISSRs algorithm are illustrated in rectangle boxes to demonstrate overlaps of the enhancers with TFs. Coverage plots of RNA-Seq data in ES cells and used features are shown at the bottom.
Chen et al. BMC Genomics 2012 13:152 doi:10.1186/1471-2164-13-152