Table 9

List of genes with altered expression according to microarray analysis related to endocytosis KEGG pathway

KEGG

Gene

embryo

larvae

name

name

o.ex.

mut.

o.ex.

mut.

description


RTK

htl

down

Fgf receptor


RTK

EGFR

up

down

Egf receptor


ArfGAP

GAP69C

down

up

down

GTPase-activating protein 69C


VPS25

VPS25

down

Vacuolar protein sorting 25


beta-arrestin

krz

up

down

kurtz, β-arrestin


E3 ligase

Traf6

up

down

down

TNF-receptor-associated factor 6


E3 ligase

elgi

up

down

early girl


GRK

GPCRK 1

up

down

G protein-coupled receptor kinase 1


RTK

Ret

up

down

Ret oncogene


Cbl; E3 ligase

Cbl

up

up

up

down

ubiquitin mediated proteolysis


VPS37

CG11155

up

down

down

ESCRT-I complex subunit VPS37


PIP5K

CG17471

up

down

down

up

1-phosphatidylinositol-4-phosphate 5-kinase


CHMP4

shrb

down

up

down

up

shrub, charged multivesicular protein


Hsc70

Hspc 2

up

down

up

Heat shock protein cognate 2


FIP

nuf

down

up

down

up

nuclear fallout, Rab11 interacting protein


Epsin

lfs

up

down

up

liquid facets


endophilin

endoB

down

up

endophilin B


CHMP6

Vps20

down

up

vacuolar protein sorting 20


Clathrin

Chc

down

up

Clathrin heavy chain


TSG101

TSG101

down

up

tumor suppressor protein 101


STAM

Stam

up

signal transducing adaptor molecule


VPS28

Vps28

up

up

vacuolar protein sorting 28


PAR6

par-6

up

up

up

partitioning defective 6


Hsc70

Hspc 1

up

up

Heat shock protein cognate 1


Hsc70

Hsp 68

up

up

Heat shock protein 68


RTK

Pvr

up

up

PDGF- and VEGF-receptor related


ARFGTPase

CG7435

up

up

ADP ribosylation factor 84F


ArfGAP

CG30372

up

up

SH3 domain, ANK repeat and PH domain


ArfGAP

cenB1A

up

up

centaurin beta 1A


VPS4

Vps4

up

up

vacuolar protein sorting 4


CHMP2

CG14542

up

up

charged multivesicular body protein 2A


CHMP2

CG4618

up

up

charged multivesicular body protein 2B


MVB12

CG7192

up

up

ESCRT-I complex subunit MVB12


Hrs

Hrs

up

up

HGF regulated tyrosine kinase substrate


PAR3

baz

up

up

bazooka, partitioning defective 3


VTA1

CG7967

up

up

vacuolar protein sorting-associated protein


CHMP5

CG6259

up

charged multivesicular body protein 5


CHMP1

CG4108

up

charged multivesicular body protein 1


ArfGAP

cenG1A

up

centaurin gamma 1A


Rab11

Rab 11

up

Rab-protein 11


Significant alterations in gene expression from wild type are shown by word code; "up" represents upregulation and "down" downregulation of gene expression. Gene name stands for the particular homologue gene name in Drosophila. Notice that the same KEGG identifier can lead to several different genes in Drosophila. The according coloured scheme for endocytosis KEGG pathway is presented in Figure 4.

Palgi et al. BMC Genomics 2012 13:134   doi:10.1186/1471-2164-13-134

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