Proteogenomic query. VESPA evaluates the imported peptides against all potential ORFs in the genome. A search quickly highlights regions of interest with at least two orphan peptides; these can be exported for further analyses. This example shows a potential mis-annotation of the start site of an ORF in the Y. pestis pestoides F genome (accession CP000668).
Peterson et al. BMC Genomics 2012 13:131 doi:10.1186/1471-2164-13-131