Open Access Research article

A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains

Lifu Song14, Padhmanand Sudhakar1, Wei Wang1*, Georg Conrads2, Anke Brock2, Jibin Sun1, Irene Wagner-Döbler3 and An-Ping Zeng1*

Author Affiliations

1 Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Hamburg, Germany

2 Division of Oral Microbiology and Immunology, Department of Operative and Preventive Dentistry & Periodontology, RWTH Aachen University, Aachen, Germany

3 Group Microbial Communication, Division of Microbial Pathogenesis, Helmholtz-Centre for Infection Research, Inhoffenstr 7, 38124, Braunschweig, Germany

4 Tianjin Institute of Industrial Biotechnology, Chinese Academy of Science, Tianjin 300308, Peoples Republic of China

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BMC Genomics 2012, 13:128  doi:10.1186/1471-2164-13-128

Published: 4 April 2012

Additional files

Additional file 1:

Multiple sequence alignment of the allelic HK proteins belonging to the TCS-14 cluster. smd|00044 and smd|00045 from S. mutans KK21; sme|00049 from S. mutans KK23; smc|00046 from S. mutans 5DC8; SMU.44 and SMU.45 from S. mutans UA159; GI|290579565 from S. mutans NN2025. The splitting of the alleles into two separate proteins in the strains S. mutans KK21 and S. mutans UA159 can be observed.

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