Transcript abundance of cellulase and hemicellulase genes in wild type and mutant strains upon growth on cellulose. (A) Genes encoding cellulases for which their contribution to cellulase activity has been evaluated , and this study. (B) Genes encoding hemicellulases for which their contribution to cellulase activity has been evaluated . The suffix (P) indicates positive effect on efficiency of the secreted cellulase mixture, (N) indicates a negative effect on the secreted cellulase mixture. (C) Hierarchical clustering of gene regulation patterns in wild type and mutant strains as analyzed using HCE3.5 with the average linkage (UPGMA) method and the Pearson correlation coefficient as distance measure.
Schmoll et al. BMC Genomics 2012 13:127 doi:10.1186/1471-2164-13-127