Additional file 7.
Fold change patterns for P. atrosepticum and D. dadantii genes implicated in virulence and for their orthologs in E. coli predicted by OrthoMCL. Anaerobic growth in the presence of glucose alters expression of virulence-associated genes in both P. atrosepticum and D. dadantii. This includes genes associated with cell wall degradation and the Out system (down-regulated in D. dadantii only), T6SS (down-regulated in D. dadantii and up-regulated in P. atrosepticum), iron uptake (down-regulated in both), methyl-accepting chemotaxis and regulators associated with virulence. Fold change patterns and genome order are as follows: E. coli, P. atrosepticum and D. dadantii (see key within the figure). Each orthologous group of genes is represented by three blocks colored by fold change (dark blue: down-regulated, fold change > 3; light blue: down-regulated, fold change < 3; bright yellow: up-regulated, fold change > 3; dirty yellow: up-regulated, fold change < 3; black: no change in expression, X: ortholog absent in that organism). Genes are represented by their symbols, or by ASAP feature IDs (especially for strain-unique genes) or by OrthoMCL group designations ("G" followed by number).
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Babujee et al. BMC Genomics 2012 13:110 doi:10.1186/1471-2164-13-110