Table 2

Representative P. falciparum proteins that are associated with the regulated intramembrane proteolysis (RIP) network.

Protease family

Accession number of protease

Associated Protein accession number

Annotation


A22 (presenilin family)

PF14_0543

PFI0150c

putative retrieval receptor for endoplasmic reticulum membrane proteins


PF13_0280

ER lumen protein retaining receptor


MAL13P1.231

Sec61 alpha subunit, PfSec61


PFB0450w

secretory complex protein 61 gamma subunit


PF11_0447

putative translation initiation factor eIF-1A


PF10_0077

putative eukaryotic translation initiation factor 3 subunit 7


PFL0310c

putative eukaryotic translation initiation factor 3 subunit 8


PFL0335c

putative eukaryotic translation initiation factor 5


PFE1405c

putative eukaryotic translation initiation factor 3, subunit 6


PFC0870w

putative elongation factor 1 (EF-1)


MAL8P1.48

putative splicing factor


PFB0550w

putative peptide chain release factor subunit 1


PF07_0034

cloroquine resistance associated protein Cg3 protein


PF13_0022

cyclin


S54 (Rhomboid family)

PF11_0150

PF11_0344

apical membrane antigen 1


PF11_0486

merozoite adhesive erythrocytic binding protein


PFA0125c

erythrocyte binding antigen-181


MAL13P1.60

erythrocyte binding antigen-140


MAL7P1.176

erythrocyte binding antigen-175


MAL13P1.176

reticulocyte binding protein 2 homolog b


M50 (S2P protease family)

PF13_0028

PF13_0287

adenylosuccinate synthetase


PF10_0317

PFB0260w

putative proteasome 26S regulatory subunit


PFF0940c

putative cell division cycle protein 48 homolog


Lilburn et al. BMC Genomics 2011 12(Suppl 5):S9   doi:10.1186/1471-2164-12-S5-S9

Open Data