Table 1

Representative P. falciparum proteins that are associated with PF10_0111, a putative 20S proteasome beta subunit with the highest connectivity. Protein-protein interactions revealed by yeast 2-hybrid assays are italicized.

Functional description

Protein accession number

Annotation


Nucleotide binding

PFL2345c

tat-binding protein homolog


Cell cycle regulation

MAL13P1.337

putative Skp1 family protein


Transcriptional regulation

PF11_0293

putative multiprotein bridging factor type 1


PF11_0477

CCAAT-box DNA binding protein subunit B


Translation

PF13_0346

putative 60S ribosomal protein L40/UBI

PF14_0141

putative 60S ribosomal protein L10

PF11_0447

putative translation initiation factor eIF-1A

PFC0870w

putative elongation factor 1 (EF-1)

PFE0350c

60S ribosomal protein L4

PF14_0270

putative apicoplast ribosomal protein L15 precursor

PF11_0245

putative translation elongation factor EF-1, subunit alpha


Protein transport

PFL2060c

rab specific GDP dissociation inhibitor


Protein modification

MAL7P1.19

putative ubiquitin transferase


Surface antigens

PF10_0345

merozoite surface protein 3

PF10_0345

merozoite surface protein 3

PF10_0348

duffy binding-like merozoite surface protein


PFE0060w

parasite-infected erythrocyte surface protein


Unknown

MAL7P1.170

Plasmodium exported protein, unknown function


Lilburn et al. BMC Genomics 2011 12(Suppl 5):S9   doi:10.1186/1471-2164-12-S5-S9

Open Data