Resolution:
## Figure 2.
Change point comparison between the given and redefined cutoffs for endpoint F. A. Change point comparison. Two parts in the figure; the upper one is for posterior mean, and the lower part
for the posterior probability. In the upper part, the blue solid lines and the translucent
skew ellipses refer to the change point chart of the cutoff 730 days (2*365) given
by MAQC-II project, while the others refer to the change point chart with the redefined
cutoff 1,561. Posterior mean for the given cutoff is linear scaled to the range of
that for the redefined cutoff. The boxplot in the left side of the change point charts
represent the ranges of the first component values of the OS negative samples. The
larger points represent the unpredictable samples. The skew elliptical ones in purple
and the circle ones in orange represent the corresponding positions in the charts
with given cutoff and redefined cutoff, respectively. In the posterior probability
part of the figure, the dashed lines are the reference lines of the maximum posterior
probability values. B. Kaplan-Meier survival curve. Six Kaplan-Meier survival curves are shown in the figure for six datasets, including
training, test and training-test combined dataset for both EFS and OS endpoint. Three
EFS associated curves (blue, green, wheat) are more sloping than OS associated curves
(purple, yellow, red) and underneath the OS associated curves.
Zhao |