Table 2

Simulated metagenomic sample

Species

Coverage

Abundance

Genome Size

# 16S rRNA


Bifidobacterium bifidum PRL2010

25

50%

2.2Mbp

3 copies

Bacteroides fragilis NCTC 9343

10

20%

5.1Mbp

6 copies

Staphylococcus aureus USA300

5

10%

2.8Mbp

5 copies

Enterococcus faecalis V583

5

10%

3.2Mbp

4 copies

Clostridium difficile 630

5

10%

4.2Mbp

11 copies


To evaluate the performance of different approaches in estimating the bacterial composition, we have created a simulated metagenomic sample consisting of 5 species with 100bp reads. ”Coverage” indicates the depth of the coverage of the simulated reads in the simulated sample for the genomes.

Liu et al. BMC Genomics 2011 12(Suppl 2):S4   doi:10.1186/1471-2164-12-S2-S4

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