Table 4

GO-term enrichment of genes over-expressed in the African population

ID

Ontology

Term

P-value


GO:0004558

MF

Alpha-glucosidase activity

0.006

GO:0004806

MF

Triglyceride lipase activity

0.021

GO:0003697

MF

Single-stranded DNA binding

0.021

GO:0019201

MF

Nucleotide kinase activity

0.021

GO:0004129

MF

Cytochrome-c oxidase activity

0.036

GO:0019318

BP

Hexose metabolic process

0.005

GO:0009586

BP

Rhodopsin mediated phototransduction

0.006

GO:0048814

BP

Regulation of dendrite morphogenesis

0.009

GO:0014866

BP

Skeletal myofibril assembly

0.015

GO:0048139

BP

Female germ-line cyst encapsulation

0.015

GO:0035075

BP

Response to ecdysone

0.025

GO:0006119

BP

Oxidative phosphorylation

0.028

GO:0012502

BP

Induction of programmed cell death

0.032

GO:0006631

BP

Fatty acid metabolic process

0.035

GO:0007015

BP

Actin filament organization

0.035

GO:0030713

BP

Ovarian follicle cell stalk formation

0.036

GO:0016028

CC

Rhabdomere

0.018

GO:0044429

CC

Mitochondrial part

0.025

GO:0016459

CC

Myosin complex

0.025

GO:0030425

CC

Dendrite

0.035


In cases where multiple, related terms within a GO hierarchy were significant, only a single term is given. The complete list is provided in Additional file 3. Ontology abbreviations are: MF, molecular function; BP, biological process; CC, cellular compartment. P-values were determined by a hypergeometric test with Benjamini-Hochberg multiple-test correction.

Müller et al. BMC Genomics 2011 12:81   doi:10.1186/1471-2164-12-81

Open Data