Table 3

Microarray and RT-qPCR results for the male hypo+ and male hypo++ treatment groups.

Microarray

RT-qPCR


Gene

Group

FC

p-value

FC

p-value


Slc25a45

Hypo+

1.5

0.000

1.6

0.314

Hypo++

2.4

0.000

Hectd3

Hypo+

*1.4

0.000

*2.4

0.026

Hypo++

1.7

0.005

H01Rik

Hypo+

1.3

0.026

2.8

0.011

Hypo++

1.4

0.008

Tor1a

Hypo+

1.3

0.026

1.6

0.117

Hypo++

1.1

0.501

Auts2

Hypo+

2.5

0.000

5.3

0.006

Hypo++

5.6

0.002

Serpina9

Hypo+

*-1.9

0.000

Hypo++

-5.0

0.000

Sned1

Hypo+

1.5

0.000

2.4

0.027

Hypo++

2.4

0.041

Trim24

Hypo+

1.5

0.000

2.9

0.398

Hypo++

1.5

0.352

Ihh

Hypo+

*-1.2

0.047

Hypo++

-2.0

0.041


The hypo++ group was not included in the microarray analysis. The fold-changes represent treated relative to control animals; for RT-qPCR data n = 5 for each group. Fold-changes (FC) and p-values are in bold when p ≤ 0.05. Asterisks (*) denote that the data were taken from female pups due to the absence of significant data from male pups. H01Rik corresponds to 2310003H01Rik. Absence of data for RT-qPCR values were because of undetectable signal due to low expression level.

Paquette et al. BMC Genomics 2011 12:634   doi:10.1186/1471-2164-12-634

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