Table 2

Microarray and RT-qPCR results for known TH-regulated genes.

Microarray

RT-qPCR


Gene

Group

FC

p-value

FC

p-value


Male Pups

Thrsp

Hypo

-2.8

0.036

-5.0

0.032

Hyper

1.6

0.999

2.4

0.170

Dio1

Hypo

-2.6

0.000

-4.9

0.015

Hyper

1.3

0.999

1.5

0.029

Me1

Hypo

-1.4

0.379

-1.4

0.099

Hyper

1.3

0.632

1.5

0.017

Female Pups

Thrsp

Hypo

-2.7

0.000

-5.0

0.033

Hyper

2.4

0.019

4.6

0.010

Dio1

Hypo

-3.2

0.000

-7.8

0.001

Hyper

1.2

0.983

1.5

0.008

Me1

Hypo

-1.4

0.045

-1.3

0.143

Hyper

1.3

0.095

1.7

0.002


Fold-changes are presented for treated animals relative to control animals; n = 4 for all groups except for hyper, where n = 5. Fold-changes (FC) and p-values are in bold when p ≤ 0.05.

Paquette et al. BMC Genomics 2011 12:634   doi:10.1186/1471-2164-12-634

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