Table 2 |
|||||
|
Microarray and RT-qPCR results for known TH-regulated genes. |
|||||
|
Microarray |
RT-qPCR |
||||
|
|
|||||
|
Gene |
Group |
FC |
p-value |
FC |
p-value |
|
|
|||||
|
Male Pups |
|||||
|
Thrsp |
Hypo |
-2.8 |
0.036 |
-5.0 |
0.032 |
|
Hyper |
1.6 |
0.999 |
2.4 |
0.170 |
|
|
Dio1 |
Hypo |
-2.6 |
0.000 |
-4.9 |
0.015 |
|
Hyper |
1.3 |
0.999 |
1.5 |
0.029 |
|
|
Me1 |
Hypo |
-1.4 |
0.379 |
-1.4 |
0.099 |
|
Hyper |
1.3 |
0.632 |
1.5 |
0.017 |
|
|
Female Pups |
|||||
|
Thrsp |
Hypo |
-2.7 |
0.000 |
-5.0 |
0.033 |
|
Hyper |
2.4 |
0.019 |
4.6 |
0.010 |
|
|
Dio1 |
Hypo |
-3.2 |
0.000 |
-7.8 |
0.001 |
|
Hyper |
1.2 |
0.983 |
1.5 |
0.008 |
|
|
Me1 |
Hypo |
-1.4 |
0.045 |
-1.3 |
0.143 |
|
Hyper |
1.3 |
0.095 |
1.7 |
0.002 |
|
|
|
|||||
|
Fold-changes are presented for treated animals relative to control animals; n = 4 for all groups except for hyper, where n = 5. Fold-changes (FC) and p-values are in bold when p ≤ 0.05. |
|||||
|
Paquette et al. BMC Genomics 2011 12:634 doi:10.1186/1471-2164-12-634 |
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