Open Access Research article

Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses

Martin A Paquette12, Hongyan Dong1, Rémi Gagné1, Andrew Williams1, Morie Malowany1, Mike G Wade1 and Carole L Yauk12*

Author Affiliations

1 Environmental Health Sciences and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, 50 Colombine Driveway, Ottawa, Ontario, K1A 0K9, Canada

2 Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6, Canada

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BMC Genomics 2011, 12:634  doi:10.1186/1471-2164-12-634

Published: 29 December 2011

Additional files

Additional file 1:

Altered genes in male pups, with a FDR-adjusted p < 0.05 in at least one of the treatment conditions.

Format: XLS Size: 83KB Download file

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Additional file 2:

Altered genes in female pups, with a FDR-adjusted p < 0.05 in at least one of the treatment conditions.

Format: XLS Size: 117KB Download file

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Open Data

Additional file 3:

The five most affected pathways, using the list of all significant genes (significant in at least one treatment condition), along with the names of the genes that were affected by TH treatment within the pathway.

Format: XLS Size: 26KB Download file

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Open Data