Table 2

Gene ontology (GO) categories identified using IPA

Gene ontology category

P-value range

Number of genes

Inflammatory response

1.66 × 10-11 - 1.64 × 10-2

241

Cellular development

8.95 × 10-10 - 1.57 × 10-2

308

Cellular growth and proliferation

1.65 × 10-9 - 1.57 × 10-2

333

Haematological system development and function

1.65 × 10-9 - 1.64 × 10-2

279

Haematopoiesis

2.60 × 10-8 - 1.57 × 10-2

173

Tissue morphology

1.78 × 10-7 - 1.19 × 10-2

114

Cellular function and maintenance

5.44 × 10-7 - 1.65 ×10-2

138

Cell death

9.57 × 10-7 - 1.60 × 10-2

419

Cell-mediated immune response

1.06 × 10-6 - 1.25 × 10-2

109

Connective tissue disorders

1.72 × 10-6 - 5.94 × 10-3

234

Immunological disease

1.72 × 10-6 - 1.57 × 10-2

344

Inflammatory disease

1.72 × 10-6 - 1.28 × 10-2

364

Skeletal and muscular disorders

1.72 × 10-6 - 1.22 × 10-2

235

Infectious disease

1.82 × 10-6 - 1.17 × 10-2

223

Cell-to-cell signalling and interaction

8.33 × 10-6 - 1.64 × 10-2

210

Dermatological diseases and conditions

1.04 × 10-5 - 1.57 × 10-2

107

Free radical scavenging

1.23 × 10-5 - 1.23 × 10-5

14

Molecular transport

1.23 × 10-5 - 7.43 × 10-3

86

Cell signalling

2.40 × 10-5 - 7.21 × 10-5

133

Respiratory disease

2.86 × 10-5 - 1.24 × 10-2

109

Cellular compromise

3.09 × 10-5 - 1.57 × 10-2

41

Genetic disorder

3.39 × 10-5 - 1.64 × 10-2

104

Immune cell trafficking

3.51 × 10-5 - 1.64 × 10-2

163

Humoral immune response

5.08 × 10-5 - 1.19 × 10-2

78

Organismal injury and abnormalities

9.51 × 10-5 - 1.05 × 10-2

81

Tissue development

1.19 × 10-4 - 1.05 × 10-2

108

Haematological disease

1.78 × 10-4 - 1.35 × 10-2

162

Gastrointestinal disease

1.88 × 10-4 - 5.51 × 10-3

42

Hepatic system disease

1.88 × 10-4 - 1.64 × 10-2

89

Lymphoid tissue structure and development

1.94 × 10-4 - 5.94 × 10-3

5

Antigen presentation

3.42 × 10-4 -1.64 × 10-2

83

Cellular movement

3.58 × 10-4 - 1.63 × 10-2

157

Vitamin and mineral metabolism

3.59 × 10-4 - 7.21 × 10-3

74

Antimicrobial response

3.92 × 10-4 - 1.28 × 10-2

32

Hypersensitivity response

5.86 × 10-4 - 8.60 × 10-3

31

Infection mechanism

9.89 × 10-4 - 1.57 × 10-2

39

Gene expression

1.07 × 10-3 - 1.57 × 10-2

254

Hair and skin development and function

1.23 × 10-3 - 1.57 × 10-2

22

Post-translational modification

2.27 × 10-3 - 9.78 × 10-3

84

Cancer

2.51 × 10-3 - 1.57 × 10-2

385

Endocrine system development and function

2.65 × 10-3 - 2.65 × 10-3

21

Carbohydrate metabolism

3.77 × 10-3 - 3.77 × 10-3

6

Cell morphology

3.77 × 10-3 - 1.28 × 10-2

23

Lipid metabolism

3.77 × 10-3 - 7.43 × 10-3

17

Neurological disease

3.77 × 10-3 - 1.47 × 10-2

49

Small molecule biochemistry

3.77 × 10-3 - 7.43 × 10-3

23

Metabolic disease

3.91 × 10-3 - 3.91 × 10-3

7

Embryonic development

4.59 × 10-3 - 1.57 × 10-2

21

Nervous system development and function

4.59 × 10-5 - 1.18 × 10-2

8

Reproductive system disease

5.84 × 10-3 - 7.54 × 10-3

79

Cell cycle

5.94 × 10-3 - 1.18 × 10-2

20

Endocrine system disorders

5.94 × 10-3 - 5.94 × 10-3

3

Opthalmic disease

5.94 × 10-3 - 6.60 × 10-3

7

RNA post-transcriptional modification

6.04 × 10-3 - 6.04 × 10-3

13

Cardiovascular system development and function

6.68 × 10-3 - 1.30 ×10-2

19

Cell assembly and modification

6.68 × 10-3 - 1.28 × 10-2

14

Organ development

6.68 × 10-3 - 1.19 × 10-2

6

Renal and urological system development and function

1.18 × 10-2 - 1.30 × 10-2

11

Reproductive system development and function

1.18 × 10-2 - 1.18 × 10-2

4

The top ranking GO categories identified by IPA are listed according to P-values. P-value ranges are based on subcategory P-values within each parent term.

Killick et al. BMC Genomics 2011 12:611   doi:10.1186/1471-2164-12-611

Open Data