Table 2

Gene ontology (GO) categories identified using IPA

Gene ontology category

P-value range

Number of genes


Inflammatory response

1.66 × 10-11 - 1.64 × 10-2

241


Cellular development

8.95 × 10-10 - 1.57 × 10-2

308


Cellular growth and proliferation

1.65 × 10-9 - 1.57 × 10-2

333


Haematological system development and function

1.65 × 10-9 - 1.64 × 10-2

279


Haematopoiesis

2.60 × 10-8 - 1.57 × 10-2

173


Tissue morphology

1.78 × 10-7 - 1.19 × 10-2

114


Cellular function and maintenance

5.44 × 10-7 - 1.65 ×10-2

138


Cell death

9.57 × 10-7 - 1.60 × 10-2

419


Cell-mediated immune response

1.06 × 10-6 - 1.25 × 10-2

109


Connective tissue disorders

1.72 × 10-6 - 5.94 × 10-3

234


Immunological disease

1.72 × 10-6 - 1.57 × 10-2

344


Inflammatory disease

1.72 × 10-6 - 1.28 × 10-2

364


Skeletal and muscular disorders

1.72 × 10-6 - 1.22 × 10-2

235


Infectious disease

1.82 × 10-6 - 1.17 × 10-2

223


Cell-to-cell signalling and interaction

8.33 × 10-6 - 1.64 × 10-2

210


Dermatological diseases and conditions

1.04 × 10-5 - 1.57 × 10-2

107


Free radical scavenging

1.23 × 10-5 - 1.23 × 10-5

14


Molecular transport

1.23 × 10-5 - 7.43 × 10-3

86


Cell signalling

2.40 × 10-5 - 7.21 × 10-5

133


Respiratory disease

2.86 × 10-5 - 1.24 × 10-2

109


Cellular compromise

3.09 × 10-5 - 1.57 × 10-2

41


Genetic disorder

3.39 × 10-5 - 1.64 × 10-2

104


Immune cell trafficking

3.51 × 10-5 - 1.64 × 10-2

163


Humoral immune response

5.08 × 10-5 - 1.19 × 10-2

78


Organismal injury and abnormalities

9.51 × 10-5 - 1.05 × 10-2

81


Tissue development

1.19 × 10-4 - 1.05 × 10-2

108


Haematological disease

1.78 × 10-4 - 1.35 × 10-2

162


Gastrointestinal disease

1.88 × 10-4 - 5.51 × 10-3

42


Hepatic system disease

1.88 × 10-4 - 1.64 × 10-2

89


Lymphoid tissue structure and development

1.94 × 10-4 - 5.94 × 10-3

5


Antigen presentation

3.42 × 10-4 -1.64 × 10-2

83


Cellular movement

3.58 × 10-4 - 1.63 × 10-2

157


Vitamin and mineral metabolism

3.59 × 10-4 - 7.21 × 10-3

74


Antimicrobial response

3.92 × 10-4 - 1.28 × 10-2

32


Hypersensitivity response

5.86 × 10-4 - 8.60 × 10-3

31


Infection mechanism

9.89 × 10-4 - 1.57 × 10-2

39


Gene expression

1.07 × 10-3 - 1.57 × 10-2

254


Hair and skin development and function

1.23 × 10-3 - 1.57 × 10-2

22


Post-translational modification

2.27 × 10-3 - 9.78 × 10-3

84


Cancer

2.51 × 10-3 - 1.57 × 10-2

385


Endocrine system development and function

2.65 × 10-3 - 2.65 × 10-3

21


Carbohydrate metabolism

3.77 × 10-3 - 3.77 × 10-3

6


Cell morphology

3.77 × 10-3 - 1.28 × 10-2

23


Lipid metabolism

3.77 × 10-3 - 7.43 × 10-3

17


Neurological disease

3.77 × 10-3 - 1.47 × 10-2

49


Small molecule biochemistry

3.77 × 10-3 - 7.43 × 10-3

23


Metabolic disease

3.91 × 10-3 - 3.91 × 10-3

7


Embryonic development

4.59 × 10-3 - 1.57 × 10-2

21


Nervous system development and function

4.59 × 10-5 - 1.18 × 10-2

8


Reproductive system disease

5.84 × 10-3 - 7.54 × 10-3

79


Cell cycle

5.94 × 10-3 - 1.18 × 10-2

20


Endocrine system disorders

5.94 × 10-3 - 5.94 × 10-3

3


Opthalmic disease

5.94 × 10-3 - 6.60 × 10-3

7


RNA post-transcriptional modification

6.04 × 10-3 - 6.04 × 10-3

13


Cardiovascular system development and function

6.68 × 10-3 - 1.30 ×10-2

19


Cell assembly and modification

6.68 × 10-3 - 1.28 × 10-2

14


Organ development

6.68 × 10-3 - 1.19 × 10-2

6


Renal and urological system development and function

1.18 × 10-2 - 1.30 × 10-2

11


Reproductive system development and function

1.18 × 10-2 - 1.18 × 10-2

4


The top ranking GO categories identified by IPA are listed according to P-values. P-value ranges are based on subcategory P-values within each parent term.

Killick et al. BMC Genomics 2011 12:611   doi:10.1186/1471-2164-12-611

Open Data