Additional file 4.

Supplementary material S4. Scatter plots of fold-changes between tumour duplicates and replicate pools. These plots each show the magnitude of the change in expression between technical replicates introduced by the runs and show how well correlated such changes are between the Pool/tumour-duplicates. In the figure, the pre-treatment tumour duplicate are coloured blue and post-treatment are green; probes that are differentially regulated, up or down, at least two-fold due to the different runs are highlighted in each plot (red points). Note that most of the samples with a duplicate on chip 22 are subject to a greater magnitude of variation than samples with a duplicate on chip 21.

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Kitchen et al. BMC Genomics 2011 12:589   doi:10.1186/1471-2164-12-589