SOS response is uniquely associated with thymineless induced lethality across treatment regimens and growth conditions. Heatmap of gene set scores associated with TMP treatment and thymineless death (TLD). Blue and yellow color refers to down-regulation and up-regulation of gene sets respectively. Condition labels are as described in Table 1. dRP: deoxyribosephosphate; SS: supercoiling; PBP: periplasmic binding proteins.
Sangurdekar et al. BMC Genomics 2011 12:583 doi:10.1186/1471-2164-12-583