Table 2

Genes for which RNA level is controlled by the two proximal and distal regions in interaction similarly to the adiposity phenotype

Classical Model

Interaction Model

Test Lean1/lean2


oligo ID

HGNC

corr

location

maxLRT

location

maxLRT

DE

p-value


RIGG00027

BPNT1

-0.36

182

9.6*

95

9.8+

-/+

+

RIGG05332

NULL

-0.39

178

6.3+

77

11.5*

-/+

*

RIGG07405

P4HA2

-0.38

185

7.3+

73

12.0*

-/+

+

RIGG12578

NULL

-0.58

158

11.7*

86

9.3+

+/-

+


For each gene, are given the oligonucleotide identifier (oligo ID), the HGNC abbreviation (HGNC), the Pearson correlation with the abdominal fatness (corr), the maximum LRT location in cM and the maximum LRT (maxLRT) using either the classical model or the interaction model. The two last columns are related to the statistical test comparing the expression between the lean1 and the lean2 subtypes: the differential expression between the two subtypes (DE = lean1/lean2) and the p-value associated are indicated. * and +: p-value at the chromosome level <0.05 and <0.1 respectively.

Blum et al. BMC Genomics 2011 12:567   doi:10.1186/1471-2164-12-567

Open Data