Trans ceQTLs in noncoding regions are not explained by recently discovered functional elements. (A) Venn diagram of the number of noncoding ceQTLs in human at FDR < 0.25 that can be accounted for by lincRNAs, novel genes and ultra conserved regions. For example, 10 noncoding ceQTL blocks contain lincRNAs, one of which overlaps with noncoding ceQTL blocks containing ultra conserved regions. (B) The majority of the 325 noncoding ceQTL blocks in human at FDR < 0.25 do not contain lincRNAs, novel genes or ultra conserved regions. (C) Number of noncoding ceQTL blocks in mouse at FDR < 0.25 that can be explained by recently discovered genomic elements. (D) Of 370 noncoding ceQTLs in mouse, 3% can be accounted for by recently discovered functional elements.
Wang et al. BMC Genomics 2011 12:562 doi:10.1186/1471-2164-12-562