The vast majority of HNF4α binding sites in the human genome are found in Alu repeats. A. Numerical results from PBM3 described in Fig. 1 and in the text. B. Position weight matrices (PWMs) generated with Weblogo  of sequences bound by human HNF4α2 in the PBM, categorized by the type of sequence. The DR1-derived PWM was from 994 sequences bound by HNF4α2, the DR2-derived PWM from 50 sequences and the Alu-derived sequences from 66 sequences. The non canonical PWM is from Bolotin et al. .
Bolotin et al. BMC Genomics 2011 12:560 doi:10.1186/1471-2164-12-560