Open Access Research article

Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats

Eugene Bolotin123, Karthikeyani Chellappa1, Wendy Hwang-Verslues14, Jake M Schnabl1, Chuhu Yang125 and Frances M Sladek12*

Author Affiliations

1 Department of Cell Biology and Neuroscience, University of California, Riverside, Riverside, CA, 92521, USA

2 Institute for Integrative Genome Biology, University of California, Riverside, Riverside, CA, 92521, USA

3 CHORI (Children's Hospital Oakland Research Institute), 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA

4 Genomics Research Center, Academia Sinica, No. 128 Academia Road, Section 2, Nankang District, Taipei 115, Taiwan

5 Roche Diagnostics Shanghai Limited, 1045 Central Huaihai Road, Shanghai 200031, China

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BMC Genomics 2011, 12:560  doi:10.1186/1471-2164-12-560

Published: 15 November 2011

Additional files

Additional file 1:

Overrepresentation of Alu-related HNF4α binding motif (H4.141) in the human genome. Frequency profile of 217 HNF4α binding sites identified by gel shift assays and derived from the literature in the human and mouse genomes.

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Additional file 2:

Supplementary Tables. Six tables with frequencies of HNF4α binding sites in repetitive DNA, complete PBM and GO results, and primers used in this study.

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