Trans-fat alters the expression of genes associated with cardiovascular disease and development in a sex-specific manner. Functional relationship network representation of A: a subset of TFA-induced male DEGs relating to cardiovascular disease and lipid metabolism. B: subset of TFA-induced female DEGs relating to cardiovascular development and lipid metabolism (P < 0.01, stringency ≥ ± 1.5-fold change in expression).
Collison et al. BMC Genomics 2011 12:555 doi:10.1186/1471-2164-12-555