Table 3

Population-specific test on the long-term evolutionary status for the SNPs from the 890 associations from the Global Set.

Europeans (CEU)a

East Asians (CHB)a

East Asians (JPT)a

Africans (YRI)a

Replicability

ANCb (%)

DERb (%)

ANCb (%)

DERb (%)

ANCb (%)

DERb (%)

ANCb (%)

DERb (%)


≤66.67%

19017

4533

18529

4991

18623

4919

19816

3757

(n = 441)

(80.8)

(19.2)

(78.8)

(21.2)

(79.1)

(20.9)

(84.1)

(15.9)

≥66.67%

19783

5173

19271

5620

19334

5556

20789

4187

(n = 441)

(79.3)

(20.7)

(77.4)

(22.6)

(77.7)

(22.3)

(83.2)

(16.8)

p-value

4.89 × 10-5

p-value

3.19 × 10-4

p-value

1.43 × 10-4

p-value

0.0144


a CEU = North Americans (Utah) of Northern European ancestry; CHB = Chinese from Beijing; JPT = Japanese from Tokyo; YRI = Yorubans from Ibadan (Nigeria)

b ANC = SNPs with an ancestral major allele (freq ≥ 0.5); DER = SNPs with a derived major allele (freq ≥ 0.5)

Marigorta et al. BMC Genomics 2011 12:55   doi:10.1186/1471-2164-12-55

Open Data