CREB binding sites on the promoter of TACSTD2. We extracted the promoter sequence of TACSTDs from TRED (the Transcriptional Regulatory Element Database, http://rulai.cshl.edu/TRED webcite), and searched for the CREB binding sites by comparing the promoter sequences with the position weight matrix (PWM). The TRANSFAC http://www.gene-regulation.com webcite and the JASPAR http://jaspar.genereg.net/ webcite databases provide different versions of CREB binding PWM. Nevertheless, there are four potential CREB binding sites that are predicted by both of the PWMs on the promoter of TACSTD2.
Wu et al. BMC Genomics 2011 12:547 doi:10.1186/1471-2164-12-547