Table 3

List of putative Helicobacter bizzozeronii secreted proteins predicted by PSORTbv3

CDS Locus_Tag

Predicted function

Localization

Sec SP¹

Tat SP²

SpII³

H. pylori orthologue

CDS Locus_tag

HBZC1_00340

Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA

Periplasmic

+

-

-

HP1252

HBZC1_00890

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

-

-

-

(-)⁴

HBZC1_00900

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

+

-

-

(-)

HBZC1_00910

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

+

-

-

(-)

HBZC1_01330

Flagellar hook protein FlgE

Extracellular

-

-

-

HP0870

HBZC1_01540

Flagellar hook-associated protein FlgK

Extracellular

-

-

-

HP1119

HBZC1_01610

HtrA protease/chaperone protein/Serine protease

Periplasmic

+

-

-

HP1019

HBZC1_02310

Membrane-anchored cell surface protein

Extracellular

-

-

-

(-)

HBZC1_02430

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

+

-

-

(-)

HBZC1_03080

Flagellar basal-body rod protein FlgC

Periplasmic

-

-

-

HP1558

HBZC1_03090

Flagellar basal-body rod protein FlgB

Periplasmic

-

-

-

HP1559

HBZC1_04310

Nitrate reductase cytochrome c550-type subunit

Periplasmic

+

-

-

(-)

HBZC1_04340

Flagellin

Extracellular

-

-

-

HP0115

HBZC1_05160

Soluble lytic murein transglycosylase

Periplasmic

+

-

-

HP0649

HBZC1_05800

Cytochrome c551 peroxidase

Periplasmic

+

-

-

HP1461

HBZC1_05960

Putative amino-acid transporter periplasmic solute-binding protein

Periplasmic

+

-

+

HP1172

HBZC1_06690

Sel1 domain-containing protein repeat-containing protein

Extracellular

-

-

-

(-)

HBZC1_07110

Flagellar hook-associated protein FlgL

Extracellular

-

-

-

HP0295

HBZC1_07220

Hypothetical protein

Extracellular

+

-

+

(-)

HBZC1_07230

Hypothetical protein

Extracellular

-

-

+

(-)

HBZC1_07880

Hypothetical protein

Extracellular

-

-

-

(-)

HBZC1_08080

Gamma-glutamyltranspeptidase

Periplasmic

+

-

-

HP1118

HBZC1_08620

Flagellar hook-length control protein FliK

Periplasmic

-

-

-

(-)

HBZC1_08630

Flagellar basal-body rod modification protein FlgD

Periplasmic

-

-

-

HP0907

HBZC1_08640

Flagellar hook protein FlgE

Extracellular

-

-

-

HP0908

HBZC1_08800

Periplasmic nitrate reductase

Periplasmic

-

+

-

(-)

HBZC1_08840

Flagellar P-ring protein FlgI

Periplasmic

+

-

-

HP0246

HBZC1_09700

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

+

-

+

HPSH_03725

HBZC1_10550

Cytochrome c nitrite reductase subunit c552

Periplasmic

+

-

-

(-)

HBZC1_10810

trimethylamine-N-oxide reductase

Periplasmic

+

-

-

HP0407

HBZC1_10890

mJ0042 family finger

Extracellular

-

-

-

(-)

HBZC1_11140

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

+

-

-

(-)

HBZC1_11160

Superoxide dismutase

Periplasmic

-

-

-

HP0389

HBZC1_11330

YgjD/Kae1/Qri7 family protein

Extracellular

-

-

-

HP1584

HBZC1_11450

Flagellar hook-associated protein FliD

Extracellular

-

-

-

HP0752

HBZC1_12200

Hypothetical protein

Extracellular

-

-

-

(-)

HBZC1_12220

Hypothetical protein

Periplasmic

+

-

-

(-)

HBZC1_12240

Catalase

Periplasmic

-

-

-

HP0875

HBZC1_12430

Nucleoside diphosphate kinase

Extracellular

-

-

-

HP0198

HBZC1_13860

Cytochrome C553 (soluble cytochrome f)

Periplasmic

+

-

-

jhp1148

HBZC1_13880

Flagellin

Extracellular

-

-

-

HP0601

HBZC1_14010

Outer membrane protein

Extracellular

-

-

-

(-)

HBZC1_14040

Flagellar basal-body rod protein FlgG

Extracellular

-

-

-

HP1092

HBZC1_14510

TolB protein

Periplasmic

+

-

-

HP1126

HBZC1_14760

Membrane-bound lytic murein transglycosylase D

Periplasmic

+

-

-

HP1572

HBZC1_15010

Arginine decarboxylase

Periplasmic

-

-

-

HP0422

HBZC1_16410

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

-

-

-

(-)

HBZC1_16420

Hypothetical protein (sel 1 domain repeat containing protein)

Extracellular

-

-

-

(-)

HBZC1_17210

Hypothetical protein

Periplasmic

-

-

-

HPG27_960

HBZC1_17260

Endonuclease I

Extracellular

-

-

-

(-)

¹The Sec specific signal peptide predicted using SignalP-HMM (http://www.cbs.dtu.dk/services/SignalP/ webcite); probability score cut off 0,500

²The Tat specific signal peptide predicted using TatP 1.0 Server (http://www.cbs.dtu.dk/services/TatP/ webcite)

³The signal peptide SpII of lipoproteins was predicted using LipoP 1.0 Server (http://www.cbs.dtu.dk/services/LipoP/ webcite)

⁴No orthologues in H. pylori; BLASTP against nr database: two proteins with amino acid identity greater than 40% over 80% sequence length were considered homologues

Schott et al. BMC Genomics 2011 12:534   doi:10.1186/1471-2164-12-534