Table 2

Lateral genetic transfer of global regulators within the E. coli - Shigella clade.

TF name

Gene coding for the TF

Blattner number

Number of target genes

Is the corresponding protein tree concordant or discordant with the E. coli - Shigella MRP tree?

Evidence for internal recombination breakpoint(s)?


CRP

crp

b3357

435

Concordant

No

FNR

fnr

b1334

282

Concordant

No

Fis

fis

b3261

225

Concordant

No

IHF

ihfA

b1712

217

Concordant

No

IHF

ihfB

b0912

217

Discordant

No

ArcA

arcA

b4401

158

Concordant

No

H-NS

hns

b1237

144

Concordant

No

NarL

narL

b1221

114

Concordant

No

Lrp

lrp

b0889

97

Concordant

No

Fur

fur

b0683

85

Concordant

No

nsrR

nsrR

b4178

84

Concordant

No

FlhDC

flhD

b1892

79

Concordant

No

FlhDC

flhC

b1891

79

Concordant

No

CpxR

cpxR

b3912

56

Concordant

No

LexA

lexA

b4043

55

Concordant

No

NarP

narP

b2193

49

Concordant

No

ModE

modE

b0761

47

Discordant

No

NtrC

glnG

b3868

44

Discordant

No

FruR

fruR

b0080

40

Concordant

No

ArgR

argR

b3237

38

Concordant

No

PhoP

phoP

b1130

37

Concordant

No

PhoB

phoB

b0399

37

Concordant

No


Global regulators are the 20 TFs that regulate the largest number of genes in the E. coli K12 TRN.

Skippington and Ragan BMC Genomics 2011 12:532   doi:10.1186/1471-2164-12-532

Open Data