Additional file 4.

CGH analysis of additional strains with chromosome copy number variation (Figure S2). Passage of the white variant CBS7779-W2 (disomic for chr 13) in culture and analysis of black or white isolates by CGH revealed changes at additional chromosomes. The black variant W2-BB showed copy number increase for a segment of chr 12, and the white isolate W2-WB gained a segmental changes for chr 12 and chr 14. The black variant strain CBS7779-B1 was confirmed to be monosomic by CGH and additional variants were identified in culture (Figure 6). In addition, white variants of strain B1 were subsequently screened for black variants (B1-WC-B1, disomic for chr 13; B1-WC-B4, monosomic for all chromosomes).

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Hu et al. BMC Genomics 2011 12:526   doi:10.1186/1471-2164-12-526