Table 1

Allocation of dysregulated proteins in EAM rats according to their biological function

GO Biological process

Name of proteins

Accession No.

Spot No.

up-regulated (↑) down-regulated (↓)


Apoptosis

Txn

IPI00231368.5

1086

Cell communication

Txn

IPI00231368.5

1086

Anxa3

IPI00207390.9

638

Clic1

IPI00421995.1

713

Arhgdib

IPI00358463.1

837

Cabp1

IPI00558996.2

136, 148

Trim72

IPI00361208.4

309


Cell cycle

Txn

IPI00231368.5

1086

Tuba4a

IPI00362927.1

243

Tuba1a

IPI00189795.1

243

Cabp1

IPI00558996.2

136, 148

Tua1b

IPI00339167.4

243

Trim72

IPI00361208.4

309


Cellular component organization

Tpm4

IPI00210941.1

684

Tuba4a

IPI00362927.1

243

Tpm3

IPI00191354.2

684

Tpm2

IPI00187731.4

684, 685

Tuba1a

IPI00189795.1

243

Capg

IPI00464670.1

477

Tuba1b

IPI00339167.4

243

Tpm1

IPI00197888.2

614


Cellular process

Tpm4

IPI00210941.1

684

Txn

IPI00231368.5

1086

Anxa3

IPI00207390.9

638

Tuba4a

IPI00362927.1

243

Tpm3

IPI00191354.2

684

Tpm2

IPI00187731.4

684, 685

Clic1

IPI00421995.1

713

Tuba1a

IPI00189795.1

243

Capg

IPI00464670.1

477

Arhgdib

IPI00358463.1

837

Cabp1

IPI00558996.2

136, 148

Tuba1b

IPI00339167.4

243

Trim72

IPI00361208.4

309

Tpm1

IPI00197888.2

614


Developmental process

Tpm4

IPI00210941.1

684

Tuba4a

IPI00362927.1

243

Tpm3

IPI00191354.2

684

Tpm2

IPI00187731.4

684, 685

Tuba1a

IPI00189795.1

243

Capg

IPI00464670.1

477

Tuba1b

IPI00339167.4

243

Ddah2

IPI00215294.1

691

Trim72

IPI00361208.4

309

Myl2

IPI00214000.4

968

Tpm1

IPI00197888.2

614


Generation of precursor metabolites and energy

Txn

IPI00231368.5

1086

Atp5b

IPI00551812.1

318

Atp5d

IPI00198620.1

1036

Ldhb

IPI00231783.5

1112

Ndufs1

IPI00358033.1

89

Ivd

IPI00193716.1

464

Mdh1

IPI00198717.8

580, 599, 1107

Uqcrc1

IPI00471577.1

356

Idh3a

IPI00198720.1

509


Immune system process

Txn

IPI00231368.5

1086

GRP94

IPI00365985.5

53

GRP78

IPI00206624.1

107

Crp

IPI00188225.1

763

Clic1

IPI00421995.1

713

Hspb1

IPI00201586.1

814

Kng1

IPI00515829.1

136, 143, 148

Hp

IPI00382202.2

364, 568, 578, 604, 808

Hspb2

IPI00213296.1

930

Hspa8

IPI00208205.1

1108


Metabolic process

Serpina1

IPI00324019.1

859

Nme1

IPI00194404.5

994

Atp5b

IPI00551812.1

318

Hibadh

IPI00202658.1

696

Atp5d

IPI00198620.1

1036

Ldhb

IPI00231783.5

1112

Ivd

IPI00193716.1

464

Mdh1

IPI00198717.8

580, 599, 1107

Uqcrc1

IPI00471577.1

356

Bckdhb

IPI00201636.3

536

Hspb2

IPI00213296.1

930

Trim72

IPI00361208.4

309

Idh3a

IPI00198720.1

509

Dlst

IPI00551702.2

295, 384

Ckb

IPI00470288.4

373

Pcca

IPI00765682.2

105

Hsdl2

IPI00367240.3

112

Dlat

IPI00231714.3

167, 173, 183

Aldh2

IPI00197770.1

295, 297

Bckdha

IPI00365663.1

383

Pdhb

IPI00194324.2

1108

Hspa8

IPI00208205.1

126

Hspd1

IPI00339148.2

212


Regulation of biological process

Kng1

IPI00515829.1

136, 143, 148


Reproduction

Hp

IPI00382202.2

364, 568, 578, 604, 808

Trim72

IPI00361208.4

309


Response to stimulus

Txn

IPI00231368.5

1086

GRP94

IPI00365985.5

53

GRP78

IPI00206624.1

107

Crp

IPI00188225.1

763

Clic1

IPI00421995.1

713

Hspb1

IPI00201586.1

814

Kng1

IPI00515829.1

136, 143, 148

Hp

IPI00382202.2

364, 568, 578, 604, 808

Hspb2

IPI00213296.1

930

Hspa8

IPI00208205.1

126


System process

Tpm4

IPI00210941.1

684

Tpm3

IPI00191354.2

684

Tpm2

IPI00187731.4

684, 685

Apoa1

IPI00197703.2

842

Hspb1

IPI00201586.1

814

Kng1

IPI00515829.1

136, 143, 148

Hp

IPI00382202.2

364, 568, 578, 604, 808

Hspb2

IPI00213296.1

930

Trim72

IPI00361208.4

309

Myl2

IPI00214000.4

968

Ckb

IPI00470288.4

373

Tpm1

IPI00197888.2

614

Hsdl2

IPI00367240.3

112


Transport

Hpx

IPI00195516.6

95, 100, 124

Alb

IPI00191737.6

143

Gc

IPI00194097.5

254

Anxa3

IPI00207390.9

638

Tuba4a

IPI00362927.1

243

Clic1

IPI00421995.1

713

Erp29

IPI00207184.1

765

Tuba1a

IPI00189795.1

243

Apoa1

IPI00197703.2

842

Tuba1b

IPI00339167.4

243

Atp5b

IPI00551812.1

318

Atp5d

IPI00198620.1

1036

Trim72

IPI00361208.4

309


Chung et al. BMC Genomics 2011 12:520   doi:10.1186/1471-2164-12-520

Open Data