Estimation of the rate of false negatives for the Ribosome (A) and Proteasome (B) set. Red indicates an increase in signal and green indicates a decrease in signal. (A) The cytosolic ribosome screen signature is compared to the screen signatures in those cases where one dsRNA is part of the cytosolic ribosome cluster and the other is not. dsRNAs with a screen signature similar to the consensus cytosolic ribosome signature are italicized. Pearson's correlation is shown between dsRNAs that target the same gene as well as the correlation between each dsRNA and the consensus signature. (B) Similar comparison for the proteasome complex screen signature.
Booker et al. BMC Genomics 2011 12:50 doi:10.1186/1471-2164-12-50