The paternal recombination site on chromosome 1 of child 1 and 2 (CH1 and CH2, defined in Figure 1) in the GMRCL dataset were defined using the identity by descent (IBD) (A, B, D) and parent-sibling tracing (PST) (C, E) methods. The grandmother and grandfather origin of paternal recombination is indicated as GM and GF, respectively. Children with identical or not identical origin are indicated as 1 and 0, respectively. Panels D and E are the enlarged view of the 114.6 -114.7 kb region on chromosome 1 shown in panels B and C, respectively, which are indicated by the black arrows. D and E: the SNP sites (open circles) that could not be mapped to either GF or GM in the IBD method, or to either an identical or non-identical status using the PST approach, are indicated as a uninformative SNPs. The calling schema of IBD and PST methods is shown in Additional File 1. The chromosomal regions without any SNP site in the Affymetrix Genome-Wide Human SNP 6.0 arrays are marked as gray blocks (A to C).
Lee et al. BMC Genomics 2011 12:434 doi:10.1186/1471-2164-12-434