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Open Access Research article

Analysis of human meiotic recombination events with a parent-sibling tracing approach

Yun-Shien Lee, Angel Chao, Chun-Houh Chen, Tina Chou, Shih-Yee Mimi Wang and Tzu-Hao Wang*

BMC Genomics 2011, 12:434  doi:10.1186/1471-2164-12-434

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Related Algorithms

Jared Roach   (2011-09-19 14:22)  Institute for Systems Biology email

The calling schema of parent sibling tracing (Additional File 1B) shows some common heritage with algorithms such as those discussed in these two sources:

Shih MC, Whittemore AS. Allele-sharing among affected relatives:non-parametric methods for identifying genes. Stat Methods Med Res. 2001 Feb;10(1):27-55. Review. PubMed PMID: 11329690

Roach JC, Glusman G, Smit AF, Huff CD, Hubley R, Shannon PT, Rowen L, Pant KP, Goodman N, Bamshad M, Shendure J, Drmanac R, Jorde LB, Hood L, Galas DJ. Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science. 2010 Apr 30;328(5978):636-9. Epub 2010 Mar 10. PubMed PMID: 20220176; PubMed Central PMCID: PMC3037280.

Competing interests

an author of Roach, Glusman, Smit, Huff et al.


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