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Open Access Research article

Histological and transcriptome-wide level characteristics of fetal myofiber hyperplasia during the second half of gestation in Texel and Ujumqin sheep

Hangxing Ren14, Li Li13, Hongwei Su2, Lingyang Xu1, Caihong Wei1, Li Zhang1, Hongbin Li1, Wenzhong Liu2 and Lixin Du1*

Author Affiliations

1 National Center for Molecular Genetics and Breeding of Animal, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, China

2 College of Animal Science and Technology, Shanxi Agricultural University, Taigu, Shanxi, 030801, China

3 College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, 625014, China

4 Chongqing Academy of Animal Sciences, Chongqing, 402460, China

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BMC Genomics 2011, 12:411  doi:10.1186/1471-2164-12-411

Published: 14 August 2011

Additional files

Additional file 1:

Quality control and validity of the gene expression microarray. This file contains the analytic settings using GeneSpring10.0 (Agilent) and the detectable rate of Agilent Sheep Gene Expression Microarray.

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Additional file 2:

Differentially expressed (DE) genes in skeletal muscle between Texel and Ujumqin sheep at 70 d. For Additional files 2-6, the t-test was employed to identify the DE genes between Texel and Ujumqin sheep at each developmental stage using GeneSpring 10.0 (Agilent). Only those genes with p ≤ 0.05(p-value in Colum B) and an absolute twofold change or more(absolute FoldChange in Colum C) were considered DE genes for further analysis. In the "regulation" column, "up" or "down" indicates that the genes were upregulated or downregulated in Texel fetal sheep, respectively, compared with those in Ujumqin fetal sheep.

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Additional file 3:

Differentially expressed (DE) genes in skeletal muscle between Texel and Ujumqin sheep at 85 d.

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Additional file 4:

Differentially expressed (DE) genes in skeletal muscle between Texel and Ujumqin sheep at 100 d.

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Additional file 5:

Differentially expressed (DE) genes in skeletal muscle between Texel and Ujumqin sheep at 120 d.

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Additional file 6:

Differentially expressed (DE) genes in skeletal muscle between Texel and Ujumqin sheep at 135 d.

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