The validation of Toll-like receptors and IFN-stimulated genes by qRT-PCR analyses. (A) The genes in this bioset [differentially regulated by 2-fold or more (P < 0.05)] were clustered according to a hierarchical algorithm; red bars represent up-regulated levels of the 15 representative genes after H1N1 infection, including TLRs and interferon-induced genes (ISGs) which were involved in anti-viral signal molecular or effectors. (B) The genes of TLRs and interferon-induced genes (ISGs) were up-regulated at various degrees in H1N1 SwIV infected pigs compared with the normal controls.
Li et al. BMC Genomics 2011 12:398 doi:10.1186/1471-2164-12-398