Clustering and characterization of the differential expression of genes. (A) The DE genes showing clear functional annotation on PID 3 have been selected for cluster analysis which is described in methods. Amongst the DE genes on PID 3, a set of 160 genes were up-regulated and the rest of 108 genes were down-regulated. Each row represents a separate gene and each column represents a separate piglet. Color legend is on the left, the color scale ranges from saturated green for log ratios -3.0 and above to saturated red for log ratios 3.0 and above. Red indicates increased gene expression levels; green indicates decreased levels compared with normal samples. (B) Categories of annotated genes based on biological process GO term. On PID 3, the DE genes mainly clustered into 34 functional groups with varied numbers. (C) The genes showing clear functional annotation on PID 7 have been selected for cluster analysis. (D) On PID 7, the DE genes mainly clustered into 33 functional groups with varied numbers. Many categories shared the same genes.
Li et al. BMC Genomics 2011 12:398 doi:10.1186/1471-2164-12-398