Table 4

Distribution and AhR enrichment and DRE analysis of differentially expressed genes elicited by TCDD.

2 hr

4 hr

8 hr

12 hr

18 hr

24 hr

72 hr

168 hr


Number of differentially expressed genesa

Up-regulated

Total

68

255

341

218

236

287

267

719

With AhR enrichmentb

55

200

202

148

172

186

164

243

With AhR enrichmentb + DRE corec

47

168

171

126

146

156

135

181


Down-regulated

Total

18

233

116

168

105

237

261

218

With AhR enrichmentb

10

123

76

102

59

131

137

123

With AhR enrichmentb + DRE corec

6

79

49

63

30

72

79

70


a |fold-change| ≥ 1.5 and P1(t) > 0.999

b AhR enriched regions at 2 hrs with FDR < 0.01

c 5'-GCGTG-3' core sequence within AhR enriched region

Dere et al. BMC Genomics 2011 12:365   doi:10.1186/1471-2164-12-365

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