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Open Access Research article

Identification of alternative splice variants in Aspergillus flavus through comparison of multiple tandem MS search algorithms

Kung-Yen Chang12 and David C Muddiman2*

Author Affiliations

1 Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27695, USA

2 W.M. Keck FT-ICR-MS Laboratory, Department of Chemistry, North Carolina State University, Raleigh, NC 27695, USA

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BMC Genomics 2011, 12:358  doi:10.1186/1471-2164-12-358

Published: 11 July 2011

Additional files

Additional file 1:

Calculation of MS/MS FDRs. The steps for deriving the false discovery rates of peptide identifications by different search algorithms are presented here in detail.

Format: PDF Size: 95KB Download file

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Open Data

Additional file 2:

Comparison of overlapping identifications at different FDRs. Consensus decision of multiple search algorithms reached the similar overlaps regardless of the search results having the controlled or uncontrolled MS/MS FDRs.

Format: PDF Size: 98KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data