Apoptotic pathway in mammals, Drosophila and Lepidoptera. Homologs of caspases and caspase regulators across species are indicated by the same color. Initiator and effector caspases are colored in blue and red respectively. The death receptor is colored in grey, the adaptor protein in orange, the protein forming the apoptosome in yellow, the apoptotic inducers in purple, and the caspase inhibitors in brown.
Courtiade et al. BMC Genomics 2011 12:357 doi:10.1186/1471-2164-12-357