Table 2

Microarray expression profiling data for common genes

Probe

Symbol

GA

p-value

HS

p-value

pRS_p53

p-value

pRS_p21

p-value

E7

p-value

E2F_DB

p-value


208832_at

ATXN10

0.36

1E-03

0.25

3E-02

-0.18

2E-01

-0.35

2E-03

0.02

9E-01

-0.23

4E-02


228080_at

LAYN

1.04

2E-04

0.30

3E-01

-0.95

1E-03

-0.70

2E-02

-0.56

6E-02

-0.11

8E-01


219922_s_at

LTBP2/3

1.32

9E-08

0.66

5E-03

-1.04

2E-05

-1.32

3E-07

-1.19

1E-06

-1.41

4E-08


223690_at

LTBP2/3

0.75

5E-09

-0.14

3E-01

-0.52

1E-05

-0.91

2E-10

-1.27

1E-14

-1.22

3E-14


204682_at

LTBP2/3

0.57

8E-04

-0.48

8E-03

-0.39

4E-02

-0.94

1E-06

-1.62

3E-12

-2.02

4E-15


227308_x_at

LTBP2/3

0.46

5E-05

0.03

9E-01

-0.43

3E-04

-0.57

4E-06

-0.28

2E-02

-0.55

4E-06


218065_s_at

TMEM9B

0.44

1E-07

-0.11

2E-01

-0.33

6E-05

-0.38

9E-06

-0.20

1E-02

-0.18

2E-02


222507_s_at

TMEM9B

0.39

2E-04

-0.19

1E-01

-0.28

1E-02

-0.34

2E-03

-0.12

3E-01

-0.07

6E-01


Log2 fold changes in gene expression in CL3EcoR cells upon senescence arrest are indicated as GA and upon shift up of control temperature insensitive HMF3S cells, from 34°C to 38°C, as HS respectively. Also indicated are the data obtained for these genes from CL3EcoR cells in which senescence had been bypassed by silencing of p53 (pRS_p53) or p21CIP1 (pRS_p21) or by inactivation of pRB using HPV16 E7 (E7) or by expression of the dominant negative E2F-DB protein.

Rovillain et al. BMC Genomics 2011 12:355   doi:10.1186/1471-2164-12-355

Open Data