Characteristics of CL3EcoR cells. a: CL3EcoR cells are immortal at 34°C but undergo a senescence arrest upon shift up 38°C. b: Senescence is bypassed upon silencing of p21CIP1 using pRSp21F or sequestration of RB family of proteins by HPV16 E7.
Rovillain et al. BMC Genomics 2011 12:355 doi:10.1186/1471-2164-12-355