Additional file 12.

Figure S6. Pathway analysis based on the Ingenuity Pathway Knowledge base. The three best ranked networks derived from EGF-regulated genes as determined by the RankProd test were (A) Cell Death, Embryonic Development, Renal and Urological Disease (B) Amino Acid Metabolism, Post-Translational Modification, Small Molecule Biochemistry and (C) Cell Cycle, Cancer, Cardiovascular System Development and Function. Upregulated genes are indicated by red symbols and down-regulated genes by green symbols. The shape of the node denotes the main function of the protein encoded by the gene. Smooth lines indicate interaction between the products of the genes; dashed lines indicate an indirect interaction and lines with an arrow indicate an "acts on" relationship. Regulated genes are shown as grey boxes; non-regulated genes associated with the regulation of some of these genes are shown as white.

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Llorens et al. BMC Genomics 2011 12:326   doi:10.1186/1471-2164-12-326