Example of a reciprocal breakpoint pair. Schematic example of a reciprocal breakpoint pair. In this schematic representation of two parts of the mouse and human genomes (blue rectangles represent synteny blocks), a simple rearrangement is represented: the inversion of the synteny block B. Following the definition of breakpoint pairs, looking at the mouse breakpoint (Am - Bm), the two human breakpoints (Ah - Bh) and (Bh - Ch) are grouped together (in red). Then, looking at the mouse breakpoint (Bm - Cm), we can also group together the two human breakpoints (Ah - Bh) and (Bh - Ch) (in green). Thus these two human breakpoints cannot be grouped with any other breakpoint and are referred to as a reciprocal breakpoint pair.
Véron et al. BMC Genomics 2011 12:303 doi:10.1186/1471-2164-12-303