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Close 3D proximity of evolutionary breakpoints argues for the notion of spatial synteny

Amélie S Véron1234*, Claire Lemaitre56*, Christian Gautier123, Vincent Lacroix123* and Marie-France Sagot123*

Author Affiliations

1 Université de Lyon, F-69000 Lyon, France

2 Laboratoire Biométrie et Biologie Evolutive, CNRS, Université Lyon 1, F-69100 Villeurbanne, France

3 Equipe BAMBOO, INRIA Grenoble Rhône-Alpes, 655 avenue de l'Europe, F-38330 Montbonnot Saint-Martin, France

4 INSERM U1052, Cancerology Research Center of Lyon, Centre Léon Bérard, Lyon, France

5 Université de Bordeaux, Centre de Bioinformatique et Génomique Fonctionnelle Bordeaux, F-33000 Bordeaux, France

6 Equipe SYMBIOSE, INRIA Rennes Bretagne Atlantique, Campus de Beaulieu, F-35042 Rennes, France

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BMC Genomics 2011, 12:303  doi:10.1186/1471-2164-12-303

Published: 10 June 2011

Additional files

Additional file 1:

Supplementary Figures. This file contains the supplementary figures mentioned in the text.

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Additional file 2:

Breakpoint pair coordinates. Plain text file containing all breakpoint pair coordinates on the human genome. Coordinates correspond to human assembly of November 2005 (NCBI36 or hg18). Additional columns indicate their evolutionary origin (human, mouse or unknown), their type (R for reciprocal and NR for non-reciprocal) and if the pair was used in the present analysis (yes or no).

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