Biological network of genes linked to the canonical pathway "molecular mechanisms of cancer" that were hypomethylated (fold change >1.5) in zebrafish hepatocellular carcinoma compared to healthy liver. This diagram shows the genes that were hypomethylated in zebrafish HCC with grey shading. Additionally, orange outlines indicate the molecules associated with the hypomethylated genes via Ingenuity pathways. Direct interactions are shown as solid lines and indirect as dashed lines. Biological network analysis was performed using Ingenuity Pathway Analysis.
Mirbahai et al. BMC Genomics 2011 12:3 doi:10.1186/1471-2164-12-3