Email updates

Keep up to date with the latest news and content from BMC Genomics and BioMed Central.

Open Access Research article

Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents

Anna M Raines and Roger A Sunde*

Author Affiliations

Department of Nutritional Sciences, University of Wisconsin, 1415 Linden Drive, Madison, WI 53706 USA

For all author emails, please log on.

BMC Genomics 2011, 12:26  doi:10.1186/1471-2164-12-26

Published: 12 January 2011

Additional files

Additional file 1:

Supplemental Figure S1. qRT-PCR and microarray expression for selected genes up-regulated by Se-deficiency.

Format: PDF Size: 151KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

Supplemental Figure S2. qRT-PCR and microarray expression for genes regulated by 2 μg Se/g diet.

Format: PDF Size: 179KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

Supplemental Table S1. List of known Nrf2-regulated transcripts with altered expression in rats fed 5 μg Se/g diet.

Format: PDF Size: 44KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 4:

Supplemental Table S2. Full list of biological processes enriched in genes removed from the original toxic Se data set due to overlap with genes altered by general toxicity and/or calorie restriction.

Format: PDF Size: 24KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data