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An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Ainhoa Ruiz-Aracama13*, Ad Peijnenburg13, Jos Kleinjans23, Danyel Jennen23, Joost van Delft23, Caroline Hellfrisch1 and Arjen Lommen13

Author Affiliations

1 RIKILT-Institute of Food Safety, Wageningen University and Research Centre, P.O. Box 230, 6700 AE, Wageningen, The Netherlands

2 Department of Health Risk Analysis and Toxicology, P.O. Box 616, 6200 MD Maastricht University, Maastricht, The Netherlands

3 Netherlands Toxicogenomics Centre, The Netherlands

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BMC Genomics 2011, 12:251  doi:10.1186/1471-2164-12-251

Published: 20 May 2011

Additional files

Additional file 1:

PDF file containing Figures S1, S2, S3, S4 and S5 and Tables S1, S2, S3, S4, S5 and S6, mentioned in the text.

Format: PDF Size: 711KB Download file

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Open Data

Additional file 2:

    Metadata and NMR raw data:
ZIP file containing: -All NMR raw data (in JCAMP-DX format ".dx") -The metadata on NMR (polars & apolars), LC-MS and GC-MS data sets (as Tab delimited files ".txt").

Format: ZIP Size: 10MB Download file

Open Data