Table 3

Enriched TFBSs.

TF

Description

Cromo-some

P-Value

Binding motif

Strand


E2F1

E2F transcription factor 1

chr20

9.3*10-18

[C/t][C/a][G/c]C[c/a][C/g][G/c][C/T][G/c]A

-

RUNX1

runt-related transcription factor 1

chr21

4.0*10-18

[C/a/t][T/a/g][G/C]{A}[G/c]{A}T[C/A][G][C/a/t/g]

+

STAF/

PAX2

paired box 2

chr10

8.4*10-18

[A/g][A/g]A[C/T/a][T/g/a][T/c][C/t][C/g][C/a]

+

STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

chr17

8.4*10-17

GAA[A/T][C/T]G[C/T][C/g/t][A/T][C/T/g]

+


Binding motifs have been represented using the IUPAC nomenclature and incorporating lower case for low frequency bases.

Vilardell et al. BMC Genomics 2011 12:229   doi:10.1186/1471-2164-12-229

Open Data