Table 1

Predominant functional annotations obtained for genes found in selected clusters from Figure 2

Cluster1

Functional categories2

TF3

Selection of genes


II

Carbohydrate metabolism

Energy reserve metabolic processes

Oxidative phosphorilation

Utilization of amino acids as N source

Glutamate pool management

Amino acid transport

STRE element

Msn2p

Msn4p

Adr1p

Sut1p

DAL2-4, DAL82, DUR1,2, PUT2, GDH2, GDH3, GAP1, UGA4


V

Generation of precursor metabolites and energy

Trans-membrane transport

Pleiotropic drug resistance

Amino acid biosynthesis and transport

Adr1p

SNF1, JEN1, CAT8, ADR1, MAL31, HXT5, AZR1, PDR10, YOR1, CRS5, TPO2, TPO3, MUP3, STR3, MET32, PUT4


X

Sugar transport

Pheromone signaling

Mating

Meiotic recombination

No enrichment

MAL11, MPH2, BAR1, STE2, STE6, PRM8, ASG7, FUS1, GPA1, MFA2, STE18, HO, REC102, SPO11


XII

Response to toxins

Nitrogen catabolite repression

No enrichment

AAD4, AAD6, AAD14, AAD16, ADH7, DAL80


XIII

Sterol metabolism

Thiamine biosynthesis

Cell wall composition

Iron homeostasis

Pleiotropic drug resistance

Mot3p

Nrg1p

Aft2p

Cin5p

DAN1-DAN4, TIR4, PAU1-PAU6, ARE1, HES1, FET4, PDR11


1Clusters highlighted in Figure 2A; 2Derived from GO term enrichment analysis (p-value < 0.05); 3Obtained from enrichment analysis for transcription factor binding site in the gene promoter region (p-value < 0.05, adjusted with Bonferroni multiple tests correction).

Carreto et al. BMC Genomics 2011 12:201   doi:10.1186/1471-2164-12-201

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