Figure 2.

Raw and normalized coverage data. Data for region of BRCA1 on chr17 where all samples represented are diploid. Mean and standard deviation (SD) for raw coverage across one lane (12 subjects) shown in top two panels. The third and fourth panels show signal-to-noise ratio for the raw and normalized data. Signal-to-noise was calculated as mean/SD for each base. The final panel shows mean and standard deviation for the ratio data from the 12 individuals across the region.

Nord et al. BMC Genomics 2011 12:184   doi:10.1186/1471-2164-12-184
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