Table 2

Differentially expressed genes shared between liver and heart in hibernating bears

Gene Symbol

Gene Name

P,

Liver

log2FC,

Liver

P,

Heart

log2FC,

Heart


Fatty Acid Catabolism (4 genes)

Aarsd1

Alanyl-tRNA synthetase domain containing 1

0.006

0.638

0.006

0.838

Acadm

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor

0.001

0.510

<0.001

1.138

Acadvl

Acyl-Coenzyme A dehydrogenase, very long chain

0.001

0.842

<0.001

0.747

Hadha

Trifunctional enzyme alpha subunit, mitochondrial precursor

0.007

0.586

0.008

0.556

Protein Biosynthesis (13 genes)

Rps18

40S ribosomal protein S18

0.001

0.899

0.002

1.144

Rps29

Ribosomal protein S29

0.006

0.802

0.001

0.843

Rbm3

RNA binding motif protein 3

<0.001

2.681

<0.001

2.863

Rpl18a

60S ribosomal protein L18a

<0.001

0.606

0.002

0.607

Rpl22

Ribosomal protein L22

0.006

1.398

0.004

0.923

Rpl24

Ribosomal protein L24

0.005

0.935

0.003

0.725

Rpl27a

Ribosomal protein L27a-like

0.004

1.349

0.008

0.927

Rpl30

Ribosomal protein L30

0.004

0.862

0.002

1.010

Rpl35a

60S ribosomal protein L35a

0.001

0.937

<0.001

1.857

Rpl7

60S ribosomal protein L7

0.008

0.767

<0.001

1.243

Rplp2

60S acidic ribosomal protein P2

0.003

1.627

0.001

0.732

Rps23

Ribosomal protein S23

<0.001

1.213

0.001

1.793

Rps24

Ribosomal protein S24

0.008

0.802

0.002

1.000

Amino Acid Catabolic Processes (3 genes)

Aldh6a1

Aldehyde dehydrogenase 6 family, member A1

0.006

-1.086

0.001

-0.893

Got1

Aspartate aminotransferase

<0.001

-1.014

0.002

-0.644

Lap3

Leucine aminopeptidase 3 protein

0.008

-0.943

0.001

-0.771

Other GO Categories (13 genes)

Cd2bp2

CD2 (cytoplasmic tail) binding protein 2

0.005

0.981

0.008

0.614

Cdk2

Cyclin-dependent kinase 2

0.001

0.755

0.005

0.827

Cd2bp2

CD2 (cytoplasmic tail) binding protein 2

0.005

0.981

0.008

0.614

Hnrnpa1

Heterogeneous nuclear ribonucleoprotein A1

0.004

1.418

0.006

1.048

St7

Suppression of tumorigenicity 7

0.001

0.909

0.003

0.965

Tinp1

TGF-beta-inducible nuclear protein 1

0.010

0.678

<0.001

0.813

Cyp1a2

Cytochrome P450, family 1, subfamily A, polypeptide 2

0.007

-2.290

0.005

-0.594

Phyh

Phytanoyl-CoA 2-hydroxylase

0.004

-2.105

0.008

-0.865

Gbe1

Glycogen branching enzyme

0.007

-0.641

0.002

0.838

Glrx3

Glutaredoxin-3

0.004

-0.595

0.001

1.011

Kif21a

Kinesin family member 21A

0.010

1.000

0.009

-0.504

Mnat1

Menage a trois homolog 1, cyclin H assembly factor

0.007

-0.675

0.006

1.067

Ppm1k

Protein phosphatase 1K

0.005

1.107

0.007

-0.615


Fedorov et al. BMC Genomics 2011 12:171   doi:10.1186/1471-2164-12-171

Open Data