Table 1 |
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Gene expression differences tested by microarray and real-time PCR in bear heart and liver |
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|
Gene Symbol |
Gene Name |
RT-PCR |
Microarray |
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|
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|
P |
log2FC |
P |
log2FC |
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|
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|
HEART |
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|
Acadvl |
Acyl-Coenzyme A dehydrogenase, very long chain |
0.034 |
0.122 |
<0.001 |
0.747 |
|
Dnajc8 |
DnaJ (Hsp40) homolog, subfamily C, member 8 |
0.008 |
0.270 |
<0.001 |
0.698 |
|
Gapdh |
Glyceraldehyde-3-phosphate dehydrogenase |
0.140 |
n/a |
0.008 |
0.620 |
|
Mbip |
MAP3K12 binding inhibitory protein 1 |
0.580 |
n/a |
0.001 |
0.884 |
|
Rbm3 |
RNA binding motif protein 3 |
<0.001 |
2.349 |
<0.001 |
2.863 |
|
Rpl35a |
Ribosomal protein L35a |
0.009 |
0.550 |
<0.001 |
1.857 |
|
Rpl7 |
Ribosomal protein L7 |
0.004 |
0.533 |
<0.001 |
1.243 |
|
Rps27 |
Ribosomal protein S27 |
0.009 |
0.600 |
0.001 |
0.720 |
|
Adk |
Adenosine kinase |
0.015 |
-0.164 |
0.006 |
-0.534 |
|
Aldh6a1 |
Aldehyde dehydrogenase 6 family, member A1 |
<0.001 |
-0.974 |
0.001 |
-0.893 |
|
Ank1 |
Ankyrin 1, erythrocytic |
<0.001 |
-1.234 |
<0.001 |
-1.440 |
|
Gstz1 |
Glutathione transferase zeta 1 |
0.031 |
-0.343 |
0.001 |
-0.605 |
|
Ube2v1 |
Ubiquitin-conjugating enzyme E2 variant 1 |
0.001 |
-0.327 |
0.004 |
-0.600 |
|
LIVER |
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|
Gpc3 |
Glypican 3 |
<0.001 |
2.307 |
<0.001 |
1.965 |
|
Rplp2 |
60S acidic ribosomal protein P2 |
<0.001 |
1.378 |
0.003 |
1.627 |
|
Cmtm8 |
CKLF-like MARVEL transmembrane domain-containing protein 8 |
0.170 |
n/a |
<0.001 |
1.525 |
|
Pc |
Pyruvate carboxylase |
0.130 |
n/a |
0.002 |
1.390 |
|
Crip2 |
Cysteine-rich protein 2 |
<0.001 |
1.064 |
0.001 |
1.285 |
|
A2m |
Alpha 2 macroglobulin |
0.003 |
1.287 |
0.004 |
1.249 |
|
Rpl36 |
60S ribosomal protein L36 |
0.002 |
0.963 |
0.004 |
1.223 |
|
Brp44l |
Brain protein 44-like protein |
0.002 |
1.638 |
0.009 |
1.198 |
|
Naca |
Nascent-polypeptide-associated complex alpha polypeptide variant |
<0.001 |
0.714 |
0.001 |
1.182 |
|
Fgfr2 |
Fibroblast growth factor receptor 2 precursor |
<0.001 |
1.055 |
<0.001 |
1.130 |
|
Tbca |
Tubulin cofactor a |
0.001 |
0.579 |
0.001 |
1.122 |
|
Rps6 |
Ribosomal protein S6 |
0.001 |
0.677 |
0.010 |
1.079 |
|
Comt |
Catechol-O-methyltransferase |
<0.001 |
-0.741 |
0.001 |
-1.817 |
|
Arg1 |
Arginase |
0.016 |
-1.418 |
0.009 |
-2.050 |
|
Phyh |
Phytanoyl-CoA 2-hydroxylase |
0.002 |
-1.328 |
0.004 |
-2.105 |
|
Tinag |
Tubulointerstitial nephritis antigen |
<0.001 |
-1.822 |
<0.001 |
-2.141 |
|
Ugt3a2 |
UDP glycosyltransferase 3 family, polypeptide A2 |
<0.001 |
-4.034 |
<0.001 |
-2.949 |
|
Fmo5 |
Flavin-containing monooxygenase 5 |
0.001 |
-2.631 |
0.002 |
-3.002 |
|
Pitrm1 |
Pitrilysin metalloprotease 1 |
0.027 |
-0.421 |
0.001 |
-3.360 |
|
|
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Inconsistent significance levels for some genes are in bold. |
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Fedorov et al. BMC Genomics 2011 12:171 doi:10.1186/1471-2164-12-171 |
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